SWITCHING OFF PROSTATE TUMOR GROWTH
A new study from the Universities of Nottingham and Bristol in the UK may have found a new way to halt the spread of prostate tumors. The concept works like this: Prostate cancer cells multiply by building blood vessels that, like pipelines, deliver the nutrients that fuel cancer cells that spread. What if you can blow up the pipelines? In this case, halt the ability of the new blood cells to develop.
That’s what researchers have been working on. They’ve found a molecule they call SRPK1 that is needed to form the new blood vessels. The process of building these new blood vessels is known as Angiogenesis. Halting angiogenesis means blocking the SRPK1 molecule—which in turn means blocking the ability of the prostate tumor to grow—which in turn means no growth of the tumor!
Big news if researchers can replicate in humans what they found in mice! Inhibiting SRPK1 means putting an end to the growth of the prostate tumor.
Chief investigator Professor David Bates (Division of Cancer and Stem Cells at the U of Nottingham) says: “Our results point to a novel way of treating prostate cancer and may have wider implications to be used in several types of cancers.”
Complete discussion can be found in the current journal Oncogene.